Medical Ethics
Dentistry and the opioid crisis: the wisdom tooth problem
For years dentists were among the leading prescribers of opioids to American teenagers, and the commonest reason was a wisdom tooth extraction. The evidence now says ibuprofen with paracetamol controls that pain better. It is the sharpest example in dentistry of a routine habit that turned out to cause harm.

01
What an interviewer is actually asking
Dental committees reach for this because it is their profession’s clearest case of iatrogenic harm from an ordinary, well-meant habit. Nobody set out to start anyone on opioids. Dentists prescribed what they had been taught to prescribe, for real pain, in good faith — and a measurable number of young people were harmed as a result.
Here is the version worth holding. This is not a story about bad dentists. It is a story about what happens when a routine is inherited rather than examined, and about how long it takes evidence to change a habit that everyone believes is kind. That framing is what a panel is listening for, because the same failure mode will be available to you in whatever you practise.
02
Why dentistry, and why teenagers
Three things converged. The procedure. Removal of third molars is among the most common surgical procedures performed on young people in the United States, frequently all four at once, frequently under sedation, and frequently in otherwise healthy patients in their late teens. The pain. It is genuinely painful for two or three days, peaking after the local anaesthetic wears off — precisely the window in which an anxious patient telephones out of hours. The habit. Prescribing a short course of an opioid combination was standard teaching for decades, and a prescription written on the day removed the risk of a distressed call at the weekend.
The age is what made it dangerous. First opioid exposure in adolescence is associated with a higher likelihood of later misuse than exposure in adulthood, and studies of opioid-naive young patients who received a dental opioid found a meaningful proportion still using at a year. The leftovers mattered too: a course prescribed for five days when two were needed left tablets in a bathroom cabinet, and household members were found to be at raised risk of misuse — the diversion problem that made a single prescription a family exposure rather than an individual one.
How the profession changed course
For decades
The standard course
An opioid combination is routine teaching for post-extraction pain. Dentists become one of the largest sources of opioid prescriptions to adolescents in the country.
Mid-2010s
The data arrives
Analyses of opioid-naive patients link dental prescriptions to persistent use, and comparisons with other countries show US dentists prescribing at many times the rate of their English counterparts for the same procedure.
2016 onward
Guidelines and state limits
The ADA adopts an interim opioid policy supporting limits on duration and mandatory continuing education; many states cap initial prescriptions at a few days and require checking a prescription drug monitoring programme before prescribing.
Late 2010s to 2020s
The evidence consolidates
Systematic reviews and an ADA-supported guideline conclude that ibuprofen with paracetamol is first-line for acute dental pain in most patients, performing as well or better than opioid combinations with fewer adverse effects.
Since
Prescribing falls
Dental opioid prescribing declines substantially from its peak. The remaining argument is about the minority of cases where an opioid is still appropriate, and about undertreated pain in patients who cannot take non-steroidals.
03
What the evidence actually says
The finding that changed practice is straightforward and worth being able to state precisely. For acute post-operative dental pain, a combination of ibuprofen — a non-steroidal anti-inflammatory acting on the inflammatory driver of the pain — and paracetamol, which works by a different mechanism, provides analgesia equal to or better than opioid combinations in most patients, with fewer adverse effects and no dependence risk. Two drugs acting on different pathways beat one that acts centrally and sedates.
That does not mean opioids have no place. A patient who cannot take non-steroidals — significant renal impairment, certain gastrointestinal disease, some anticoagulation situations — needs an alternative. Some surgical cases genuinely exceed what the combination controls. The current position is that an opioid should be a considered exception with the smallest effective quantity for the shortest period, not a default written alongside the extraction note.
The undertreatment risk deserves naming, because the pendulum can swing too far. Pain that is real and inadequately controlled is itself a harm, and there is evidence that some patient groups — including Black patients — have historically been undertreated for pain in emergency and dental settings. A candidate who says "never prescribe opioids" has replaced one unexamined rule with another.
Simplified; dosing and suitability are clinical decisions for a qualified prescriber.
| Compared on | Ibuprofen with paracetamol | Opioid combination |
|---|---|---|
| Mechanism | Anti-inflammatory plus central, two pathways | Central only |
| Evidence for acute dental pain | Equal or superior in most patients | No advantage in most patients |
| Adverse effects | Gastric, renal cautions | Sedation, nausea, constipation, dependence risk |
| Role now | First line | Considered exception, smallest quantity, shortest course |
04
The lesson worth taking
The generalisable point, and the one that earns marks, is about how the harm happened. Nobody was negligent in the ordinary sense. Dentists prescribed the drug they were taught to prescribe, for pain that was real, to patients who were grateful. The harm was invisible at the level of the individual consultation and only appeared in population data — which is precisely the kind of harm a conscientious clinician cannot detect by paying attention to their own patients.
That has three implications a panel will recognise. First, routine deserves periodic examination, because "this is how we do it" is not a clinical justification. Second, population-level evidence has to be able to overturn individual clinical impression, which is uncomfortable because your own patients did seem fine. Third, the profession corrected itself — through guidelines, education requirements, monitoring programmes and state limits — which is the argument for self-regulation actually working, and it is fair to say so.
05
Use it in your interview
This arrives in three shapes. The direct one: "What role has dentistry played in the opioid crisis?" The scenario one: a patient asks specifically for something stronger after an extraction. And the disguised one — "Tell me about a time medicine got something wrong" or a question about evidence-based practice.
For the direct question, give the third molar mechanism and then the correction. For the scenario, explain the evidence, offer the combination, and know when an opioid is genuinely indicated. For the disguised question, this is one of the best available answers because the profession fixed it.
The points that carry this answer
- Third molar extraction is the mechanism: a common, painful, elective procedure on teenagers, at the age when first opioid exposure carries the most risk.
- Dentists were historically the largest source of opioid prescriptions for adolescents, which is a specific and memorable fact rather than a general claim about overprescribing.
- Ibuprofen with paracetamol is first line because two pathways beat one, and it performs as well or better with fewer adverse effects — knowing the pharmacological reason beats knowing the recommendation.
- Leftover tablets made a single prescription a household exposure, which is why quantity and duration limits matter as much as the decision to prescribe at all.
- Opioids remain appropriate where non-steroidals are contraindicated, and saying so prevents the answer from becoming a new unexamined rule.
- The harm was invisible in the consultation and visible only in population data, which is the transferable lesson about routine, evidence and self-correction.
Where applicants lose points
Blaming dentists
They followed the teaching of the time for genuine pain. The interesting failure is systemic, not personal, and saying so is what shows judgement.
Saying opioids should never be prescribed
Some patients cannot take non-steroidals, and undertreated pain is its own harm with its own inequities. Absolutes replace one bad rule with another.
Missing the diversion point
Leftover tablets in a cabinet exposed household members. That is why the size of the prescription mattered, not just whether one was written.
06
Where to read more
Start with the ADA’s statement and policy on opioid prescribing, then its clinical practice guideline on managing acute dental pain, which sets out the ibuprofen and paracetamol recommendation with the evidence behind it. The CDC’s opioid prescribing guidance gives the wider context, and any of the studies of persistent use in opioid-naive dental patients is worth reading in the original for its methods.
Two pieces here sit beside this one. How a dentist is trained in America explains where prescribing habits are formed, and silver diamine fluoride is the other case of dentistry rethinking a routine. For the ethics framework, see our guide to the four pillars.
A sensible order to read them in
- The ADA policy and statement on opioid prescribing in dentistry.
- The ADA clinical practice guideline on the pharmacologic management of acute dental pain.
- One study of persistent opioid use in opioid-naive patients after dental procedures, methods section first.
- The CDC clinical practice guideline for prescribing opioids for pain, for the wider framework.
FAQ
Frequently asked questions
Because of third molar extraction — a very common, genuinely painful, elective procedure performed largely on teenagers and young adults, often removing several teeth at once. Prescribing a short opioid course was standard teaching for decades, and it avoided out-of-hours calls from patients in pain. The volume of the procedure, not any single decision, made dentistry a leading source.
Sources
Sources
Every post is checked against primary sources before it is published.
- Opioid prescribing: ADA policy and statement — American Dental Association (accessed 29 August 2026)
- Evidence-based clinical practice guideline on acute dental pain management — American Dental Association (accessed 29 August 2026)
- Clinical Practice Guideline for Prescribing Opioids for Pain — Centers for Disease Control and Prevention (accessed 29 August 2026)
- Prescription Drug Monitoring Programs — Centers for Disease Control and Prevention (accessed 29 August 2026)
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