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US Medicine · 2027 Entry

Mayo Clinic Alix School of Medicine

2027 Entry Requirements & Interview Format

Mayo Clinic Alix School of Medicine is a US MD program in Rochester, MN that takes 2027-entry applications through AMCAS. Its published class profile lists a median MCAT of 521 (range 515–525), a median GPA of 3.97, a 3.3% acceptance rate and a class of 105. The school holds a traditional interview: August 2026–January 2027. Decisions for 2027 entry: March 30, 2027.

Location
Rochester, MN, United States
Established
1972
Interviews (2027 entry)
August 2026–January 2027
Decisions (2027 entry)
March 30, 2027
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Mayo Clinic Alix School of Medicine (MD) — The iconic gothic Plummer Building tower of the Mayo Clinic in Rochester

Photo: w_lemay · CC BY-SA 2.0 · cropped

Photo: w_lemay · CC BY-SA 2.0 · Photo: Farragutful · CC BY-SA 4.0 · Photo: Jonathunder · CC BY-SA 3.0

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Full guide

How to get into Mayo Clinic Alix School of Medicine (MD) medicine

Step-by-step: entry requirements, MCAT prep, personal statement, interview format and the key deadlines.

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Interview guide

Prepare for the Mayo Clinic Alix School of Medicine (MD) interview

Format breakdown, school-specific sample questions, FAQs and prep tips from tutors who interviewed here.

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The program

What the Mayo Clinic Alix School of Medicine MD program is like

Integrated, 4 years, clinical rotations in Rochester, Minnesota; Phoenix/Scottsdale, Arizona; and Jacksonville, Florida.

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Overview

About Mayo Clinic Alix School of Medicine (MD)

Mayo Clinic Alix School of Medicine, established in 1972, is embedded within Mayo Clinic — the top-ranked hospital in the United States (US News). Students train at a world-renowned academic medical center with unparalleled access to rare and complex disease cases.

The school's small class size (~50 students in Rochester, additional students at the Arizona campus) ensures individualized mentorship and exceptional clinical exposure from Year 1.

What makes Mayo Clinic Alix School of Medicine (MD) different

Training at the number-one ranked US hospital means medical students regularly encounter rare diseases that other institutions rarely see. The collaborative team medicine model — a core Mayo principle — permeates the curriculum. Mayo's emphasis on teamwork means the interview process specifically evaluates collegiality and team-orientation over individual competition.

Mayo Clinic Alix School of Medicine (MD) course & teaching

Case-based curriculum. 4-year MD. Immersive clinical integration from Year 1 within the Mayo Clinic system. Case-based and team-based learning emphasized. Year 3–4: clinical rotations at Mayo Rochester and affiliated sites. An optional 5-year MD with a built-in research year is available.

Mayo Clinic Alix School of Medicine (MD) research strengths

Mayo Clinic Alix School of Medicine (MD) is strong in these research areas:

  • Rare and complex diseases
  • Clinical trials
  • Oncology
  • Genomic medicine
  • Patient outcomes research

How the Mayo Clinic Alix School of Medicine (MD) interview runs

Format: Two one-on-one 30-minute virtual interviews, plus a welcome session, a virtual campus tour, time with students and a Q&A

Mayo Clinic Alix School of Medicine (MD) intake

Approximately 50 students (Rochester campus) + 50 students (Arizona campus).

Where Mayo Clinic Alix School of Medicine (MD) is

Mayo Clinic Alix School of Medicine was founded in 1972 and is based in Rochester, MN.

Programmes offered:

  • Complex Disease Management
  • Internal Medicine
  • Surgical Specialties
  • Research
  • Primary Care
Practise

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These are real recordings of the interviewers you would meet, from a panel of 21 photoreal faces. Speak your answers out loud, get pressed with follow-ups, and receive rubric-scored feedback about two minutes after you finish, with a replay of your answers.

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Entry requirements

What you need to apply to Mayo Clinic Alix School of Medicine (MD)

Mayo Clinic Alix School of Medicine (MD) at a glance

Mayo Clinic Alix School of Medicine Medicine — 2027 entry at a glance
MCAT / GPA (medians)521 · 3.97 (MCAT range 515–525)
Acceptance rate3.3%
Class size105
In-state preferenceNo stated in-state preference
Interview formatTraditional interview
IntakeApproximately 50 students (Rochester campus) + 50 students (Arizona campus)
Decisions (2027 entry)March 30, 2027
Mayo Clinic Alix School of Medicine Medicine admissions profile — 2027 entry
Admission overviewBachelor's degree and MCAT required. Secondary application required. Mayo highly values teamwork, collaborative spirit, and commitment to patient-centered care, reflecting the Mayo Clinic model of collaborative medicine.
MCAT median521 (range 515–525)
GPA median3.97 overall / 3.88 science (BCPM)
Acceptance rate3.3%
Class size105
In-state preferenceNone
CASPerNot required
AAMC PREviewNot required
Holistic review emphasisTeamwork, collaborative medicine, patient-centered values, and commitment to the Mayo Clinic model.
NotesChecked 2026-09-14 against the school's own published figures (class entering in 2026): median MCAT 521; median GPA 3.97; class of 105; 180 accepted of 5,499 applicants. Not confirmed from the school's own pages: science GPA. Mayo does not always publish full class statistics publicly; ranges from AAMC FACTS and secondary sources. Interview format checked 2026-10-07 against https://college.mayo.edu/academics/mayo-clinic-alix-school-of-medicine/md-program/how-to-apply/.
Specialities offeredComplex Disease Management, Internal Medicine, Surgical Specialties, Research, Primary Care

MCAT, GPA, acceptance-rate and class-size figures are taken from Mayo Clinic Alix School of Medicine's published admissions data. Class profiles are republished each year — confirm which entering class these numbers describe before you rely on them.

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Interview

How Mayo Clinic Alix School of Medicine (MD) interviews applicants

Mayo Clinic Alix School of Medicine Medicine interview — 2027 entry
FormatTwo one-on-one 30-minute virtual interviews, plus a welcome session, a virtual campus tour, time with students and a Q&A
Interview window (2027 entry)August 2026–January 2027
Decision date (2027 entry)March 30, 2027
Tutor insight
Mayo's virtual interview day is comprehensive — interviewers probe your collaborative instincts, patient-centered values, and self-awareness at length. Unlike at research-centric schools, demonstrating enthusiasm for the team medicine philosophy and patient experience is as important as research achievements. The small class size means peer cohort dynamics matter; show that you are a genuinely collaborative, humble person who elevates those around you. If you are applying to the Rochester campus, express specific enthusiasm for the unique case complexity and rare-disease exposure available in a top-ranked hospital system.
Practice

Practise for your Mayo Clinic Alix School of Medicine (MD) interview

PrometheusQuestion Bank621 medicine questions inside

Interview questions matched to Mayo Clinic Alix School of Medicine (MD)

Two questions from our US bank that match Mayo Clinic Alix School of Medicine (MD)’s panel format. Try answering them out loud, then open Prometheus for the model answers and follow-up tips.

HardMMI · PanelQ1

Depressed Patient Refusing Amputation

A 60-year-old man with moderate depression and poorly controlled diabetes presents for an elective leg amputation recommended by his vascular surgeon to prevent death from gangrene. He tells you he refuses the operation: 'I would rather die than live without my leg.'

His wife insists he is 'not in his right mind' due to his depression and demands that you proceed with the surgery. What is your ethical and clinical obligation?

Likely follow-up · What is the legal standard for decision-making capacity in the US, and how does depression affect it?

3 expert tips in Prometheus
MediumPanelQ2

What Your Clinical Experience Revealed

From your clinical experience, whether scribing, working as an EMT or CNA, or shadowing, what surprised you about the reality of being a physician, and how did it change your understanding of the career?

Likely follow-up · Was there a moment in your clinical work that made you doubt whether medicine was right for you? What did you do with that doubt?

3 expert tips in Prometheus
Open Prometheus for Mayo Clinic Alix School of Medicine (MD)Free medicine interview question bank for Mayo Clinic Alix School of Medicine (MD) applicants →
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MCAT Strategy

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Interview preparation

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Personal statement help

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Sources

Where Mayo Clinic Alix School of Medicine (MD)'s figures come from

Checked against Mayo Clinic Alix School of Medicine's own website on 14 September 2026: our record for the school was reconciled with what it publishes there. For most US schools that is class size and interview format only, so MCAT, GPA and acceptance-rate figures remain unconfirmed.

Mayo Clinic Alix School of Medicine (MD) — official course page →Entry requirements, interview format and deadlines published by the school itself. The primary source for everything on this page.Mayo Clinic Alix School of Medicine (MD) — published admissions data →The class profile and admissions statistics this record's MCAT, GPA, acceptance-rate and class-size figures were taken from.Mayo Clinic Alix School of Medicine (MD) — published admissions data →The class profile and admissions statistics this record's MCAT, GPA, acceptance-rate and class-size figures were taken from.Mayo Clinic Alix School of Medicine (MD) — published admissions data →The class profile and admissions statistics this record's MCAT, GPA, acceptance-rate and class-size figures were taken from.
FAQ

Mayo Clinic Alix School of Medicine (MD) — frequently asked questions

Mayo Clinic Alix School of Medicine (MD) matriculants have a median MCAT of 521. The middle range of matriculants is 515–525. US schools publish medians rather than cut-offs, and committees review holistically — the MCAT is weighed alongside GPA, clinical and research experience, letters of recommendation and secondary essays.

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