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US Medicine · 2027 Entry

USC Greenville School of Medicine

2027 Entry Requirements & Interview Format

University of South Carolina School of Medicine Greenville is a US MD program in Greenville, SC that takes 2027-entry applications through AMCAS. Its published class profile lists a median MCAT of 510 (range 505–516), a median GPA of 3.71, a 4.0% acceptance rate and a class of 100. The school holds a traditional interview: September 2026–February 2027. Decisions for 2027 entry: March 30, 2027 (AAMC standard).

Location
Greenville, SC, United States
Established
2012
Interviews (2027 entry)
September 2026–February 2027
Decisions (2027 entry)
March 30, 2027 (AAMC standard)
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Full guide

How to get into USC Greenville School of Medicine (MD) medicine

Step-by-step: entry requirements, MCAT prep, personal statement, interview format and the key deadlines.

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Interview guide

Prepare for the USC Greenville School of Medicine (MD) interview

Format breakdown, school-specific sample questions, FAQs and prep tips from tutors who interviewed here.

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Overview

About USC Greenville School of Medicine (MD)

University of South Carolina School of Medicine Greenville, opened in 2012, is a public medical school and the newest MD-granting institution in South Carolina. It operates in close partnership with Prisma Health Upstate, one of the largest health systems in the Southeast.

The school trains physicians to serve the Greenville Upstate region — one of South Carolina's most rapidly growing areas — and the broader SC healthcare workforce. A small class size and newly built facilities create an intimate, collaborative learning environment with high faculty accessibility.

What makes USC Greenville School of Medicine (MD) different

USC Greenville is the newest of South Carolina's MD-granting schools, established in 2012 through a partnership between the University of South Carolina and Prisma Health (formerly Greenville Health System/Upstate). Its small class size creates an unusually collaborative learning environment.

The Greenville Upstate region is one of SC's fastest-growing areas, providing a dynamic clinical training environment across urban, suburban, and rural settings.

USC Greenville School of Medicine (MD) course & teaching

Integrated curriculum. 4-year MD. Years 1–2: integrated sciences curriculum in Greenville. Years 3–4: clinical rotations at Prisma Health Greenville Memorial, Patewood, Hillcrest, and affiliated community sites across the Upstate region. Students benefit from modern simulation facilities and close Prisma Health partnership for clinical mentoring.

USC Greenville School of Medicine (MD) research strengths

USC Greenville School of Medicine (MD) is strong in these research areas:

  • Community health
  • Rural medicine
  • Primary care workforce development
  • Health equity in the Upstate
  • Chronic disease management

How the USC Greenville School of Medicine (MD) interview runs

Format: One 50-minute virtual (Webex) interview with two members of the Admissions Evaluation Committee

USC Greenville holds a virtual interview day on Webex, on Thursdays from August to April. Each applicant has one 50-minute interview conducted by two members of the Admissions Evaluation Committee. Interviewers focus on commitment to South Carolina and the Upstate region, community service, personal motivation, and academic readiness.

The school's newer campus culture means interviewers particularly value collaborative, growth-oriented applicants comfortable with a smaller, evolving institution.

USC Greenville School of Medicine (MD) intake

Approximately 100 students per year.

Where USC Greenville School of Medicine (MD) is

University of South Carolina School of Medicine Greenville was founded in 2012 and is based in Greenville, SC.

Programmes offered:

  • Primary Care
  • Internal Medicine
  • Family Medicine
  • Community Medicine
  • Rural Medicine
Practise

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Entry requirements

What you need to apply to USC Greenville School of Medicine (MD)

USC Greenville School of Medicine (MD) at a glance

University of South Carolina School of Medicine Greenville Medicine — 2027 entry at a glance
MCAT / GPA (medians)510 · 3.71 (MCAT range 505–516)
Acceptance rate4.0%
Class size100
In-state matriculants76%
Interview formatTraditional interview
IntakeApproximately 100 students per year
Decisions (2027 entry)March 30, 2027 (AAMC standard)
University of South Carolina School of Medicine Greenville Medicine admissions profile — 2027 entry
Admission overviewBachelor's degree and MCAT required. Applications via AMCAS. South Carolina residency is strongly preferred. Community service, clinical experience, and ties to the Upstate SC region are valued. Secondary application required.
MCAT median510 (range 505–516)
GPA median3.71 overall / 3.66 science (BCPM)
Acceptance rate4.0%
Class size100
In-state preferenceStrong — primarily in-state
In-state matriculants76%
CASPerNot required
AAMC PREviewNot required
Holistic review emphasisSC residency; commitment to Upstate SC healthcare workforce; collaborative spirit; primary care orientation.
NotesEstimates from public AAMC FACTS / class-profile data; verify current cycle. Interview format checked 2026-10-07 against https://www.sc.edu/study/colleges_schools/medicine_greenville/admissions/learn_how_to_apply/interview_day/index.php.
Specialities offeredPrimary Care, Internal Medicine, Family Medicine, Community Medicine, Rural Medicine

MCAT, GPA, acceptance-rate and class-size figures are taken from University of South Carolina School of Medicine Greenville's published admissions data. Class profiles are republished each year — confirm which entering class these numbers describe before you rely on them.

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Interview

How USC Greenville School of Medicine (MD) interviews applicants

University of South Carolina School of Medicine Greenville Medicine interview — 2027 entry
FormatOne 50-minute virtual (Webex) interview with two members of the Admissions Evaluation Committee
Interview window (2027 entry)September 2026–February 2027
Decision date (2027 entry)March 30, 2027 (AAMC standard)
Post-interview chancesEstimated post-interview acceptance rate approximately 25–35%; SC ties and primary care orientation are primary selection factors.
Tutor insight
USC Greenville's newest-school status means it is still building reputation nationally — for SC residents, this translates into less competition than MUSC while still offering strong clinical training at Prisma Health Upstate. The small class size is a genuine advantage: faculty know every student, and mentorship is accessible. In interviews, show enthusiasm for being part of a growing institution — applicants who see the newer-school status as a drawback rather than an opportunity will not resonate with interviewers. The Greenville metro's rapid growth means the patient population is increasingly diverse; demonstrate awareness of the changing demographics and health needs of Upstate SC.
Practice

Practise for your USC Greenville School of Medicine (MD) interview

PrometheusQuestion Bank621 medicine questions inside

Interview questions matched to USC Greenville School of Medicine (MD)

Two questions from our US bank that match USC Greenville School of Medicine (MD)’s panel format. Try answering them out loud, then open Prometheus for the model answers and follow-up tips.

MediumMMI · PanelQ1

Three Years at a Free Clinic

You spent three years as a weekly volunteer at a free clinic serving uninsured and underinsured patients in an urban neighborhood. Over time you noticed that the same patients returned repeatedly for the same chronic conditions — hypertension, diabetes, asthma — that never seemed to improve.

What did you observe about the structural barriers these patients faced, and how did that experience influence your vision of what a physician's role should be?

Likely follow-up · How do social determinants of health — housing, food security, employment — interact with chronic disease management in underserved populations?

3 expert tips in Prometheus
MediumPanelQ2

Rural primary-care shortage and HPSAs

Large parts of rural America are designated Health Professional Shortage Areas, and the US faces a projected shortage of primary care physicians. Why is it so hard to recruit and retain physicians in rural and underserved communities, and what could realistically change that?

Likely follow-up · How do programs like the National Health Service Corps or J-1 visa waivers attempt to address this, and what are their limitations?

3 expert tips in Prometheus
Open Prometheus for USC Greenville School of Medicine (MD)Free medicine interview question bank for USC Greenville School of Medicine (MD) applicants →
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Sources

Where USC Greenville School of Medicine (MD)'s figures come from

Compiled from University of South Carolina School of Medicine Greenville's published admissions material and checked for internal consistency. Not independently re-checked against the school's own website for 2027 entry — confirm the figures with the school before you rely on them.

USC Greenville School of Medicine (MD) — official course page →Entry requirements, interview format and deadlines published by the school itself. The primary source for everything on this page.
FAQ

USC Greenville School of Medicine (MD) — frequently asked questions

USC Greenville School of Medicine (MD) matriculants have a median MCAT of 510. The middle range of matriculants is 505–516. US schools publish medians rather than cut-offs, and committees review holistically — the MCAT is weighed alongside GPA, clinical and research experience, letters of recommendation and secondary essays.

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